Chymostatin - Protease Inhibitor
Available from Peptides International

 

 Chymostatin is a cell permeable, reversible inhibitor possessing a C-terminal phenylalaninal of chymostatin which inhibits chymotrypsin. This peptide aldehyde inhibits several proteinases:

  • chymotrypsin

  • chymotrypsin-like serine proteinases

  • cysteine proteinases such as cathepsins B and G

where X = Leu (A), Val (B) or Ile (C)

working concentration: 10-100
mM

Average Molecular Weight: 604.28
form A,  MW = 607.7  B, MW = 593.7 C, MW = 607.7

Chymostatin is a mixture of several components, typically ~70% chymostatin A, ~20% chymostatin B and 5-10% chymostatin C.

Download Chymostatin PDF
 

 

CODE

Protease Inhibitor

QTY

USD

ICY-4063-v
 

Chymostatin

A Mixture of Type A, B, and C
[(S)-1-Carboxy-2-Phenylethyl]Carbamoyl-α-
[2-Iminohexahydro-4(S)-Pyrimidyl]-(S)-Glycyl-X-Phenylalaninal
X: L-Leu (Type A), L-Val (Type B), L-Ile (Type C)
[9076-44-2]
Microbial Product
Inhibitor for Chymotrypsin, Papain, and Cathepsin B/G
 

0.5 mg vial

35

ICY-4063

Chymostatin

A Mixture of Type A, B, and C
[(S)-1-Carboxy-2-Phenylethyl]Carbamoyl-α-[2-Iminohexahydro-4(S)-Pyrimidyl]-(S)-Glycyl-X-Phenylalaninal
X: L-Leu (Type A), L-Val (Type B), L-Ile (Type C)
[9076-44-2]
Microbial Product
Inhibitor for Chymotrypsin, Papain, and Cathepsin B/G

*Purity of this compound is provided at a level of around 50%.

• This compound is distributed through Peptide Institute, Inc. under the technical and scientific advice of the Microbial Chemistry Research Foundation.

25  mg
100 mg

 

173
520


Larger quantities available, please inquire.

H. Umezawa, T. Aoyagi, H. Morishima, S. Kunimoto, M. Matsuzaki, M. Hamada, and T. Takeuchi, J. Antibiotics, 23, 425 (1970). (Original)

K. Tatsuta, N. Mikami, K. Fujimoto, S. Umezawa, H. Umezawa, and T. Aoyagi, J. Antibiotics, 26, 625 (1973). (Chem. Structure)

R.L. Stein and A.M. Strimpler, Biochemistry, 26, 2611 (1987). (Inhibitory Activity)

L.A. Johnson, K.E. Moon, and M. Eisenberg, Biochim. Biophys. Acta, 953, 269 (1988). (Inhibitory Activity)

• This compound is distributed through Peptide Institute, Inc. under the technical and scientific advice of the Microbial Chemistry Research Foundation.

 

Please contact Peptides International for ordering information.
Peptides International, Inc.
PO Box 24658 Louisville, Kentucky 40224 USA
Phone: 502-266-8787 or 800-777-4779
Fax: 502-267-1FAX (1329)

Email:  peptides@pepnet.com

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